A paradigm shift within the therapy of persistent lymphocytic leukemia (CLL) has taken place over the previous decade, as therapies have progressed from offering palliative aid to inducing full remission, eradicating minimal illness and bettering survival. The event of Rituxan® (rituximab) and its use in immunochemotherapy regimens has remodeled the therapy of CLL and...
Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline.
Schistosomiasis, certainly one of 17 illnesses deemed to be uncared for by the World Well being Group, has acquired little consideration from the biopharmaceutical business. As a result of this, solely a handful of medication have been developed to deal with schistosomiasis, with just one, praziquantel, utilized in most endemic areas. Rising concern over...
Medicine patent pool–pharma philanthropy or PR?
Merck lately signed an settlement with The Medicines Patent Pool (MPP) to license mental property regarding pediatric formulations of its integrase HIV drug, raltegravir (Ral) (the ‘Settlement’). The Settlement is alleged to clear the best way for cheaper formulations to be used in growing and a few center revenue international locations and permits for...
Cardiovascular microphysiological systems (CVMPS) for safety studies – a pharma perspective
The integrative responses of the cardiovascular (CV) system are important for sustaining blood circulation to supply oxygenation, vitamins, and waste elimination for the whole physique. Progress has been made in independently growing easy in vitro fashions of two major elements of the CV system, specifically the center (utilizing induced pluripotent stem-cell derived cardiomyocytes) and...