Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline.

Schistosomiasis, certainly one of 17 illnesses deemed to be uncared for by the World Well being Group, has acquired little consideration from the biopharmaceutical business. As a result of this, solely a handful of medication have been developed to deal with schistosomiasis, with just one, praziquantel, utilized in most endemic areas. Rising concern over resistance coupled with praziquantel’s incomplete efficacy throughout all phases of the Schistosoma platyhelminth life cycle highlights the pressing want for brand spanking new medication.

The WIPO Re:Search consortium is a platform whereupon biopharmaceutical firm compounds are being repurposed to effectively and cost-effectively develop new medication for uncared for illnesses resembling schistosomiasis. This text summarizes latest clinical-stage efforts to determine new antischistosomals and highlights biopharmaceutical firm compounds with potential for repurposing to deal with schistosomiasis.

Flavonoids on the pharma-nutrition interface: Is a therapeutic index in demand?

The consumption of flavonoid-rich meals may have useful results on well being. Nevertheless, totally different lessons of flavonoids have totally different impact on illness threat and the connection between flavonoid consumption and threat of illness seemed to be non-linear. Moreover, contrarily to nutritional vitamins, there aren’t any signs of deficiency for flavonoids; due to this fact, our physique treats them like different xenobiotics. Due to this fact, a therapeutic index must be decided. Regardless of flavonoids are on the pharma-nutrition interface, medication and meals are topic to totally different regulatory frameworks and there’s no really helpful each day allowance (RDA) for flavonoids.

Comparatively little is understood in regards to the efficacy, security and underlying mechanisms of those bioactive compounds, particularly when taken in live performance with medication. Flavonoids may act each as medication and pro-drugs with pharmacological and toxicological promiscuity. As a result of low bioavailability, the gastrointestinal tract may very well be the first goal of flavonoids and metabolites. Completely different results have been noticed after acute and power consumption and bioavailability and bioactivity have excessive inter-individual variability.

Moreover, the difficulties within the design and within the interpretation of human intervention research make troublesome the institution of a therapeutic index for flavonoids. Most likely the idea of ‘personalised diet’ beforehand proposed may very well be the higher strategy. Nevertheless, regardless of extra research are wanted with the intention to set up a therapeutic index for every flavonoid subclasses, for the time being RDA of whole flavonoids may very well be between 250-400 mg/d, respecting the seasonality of meals sources.

High quality compliance within the shift from cell transplantation to cell remedy in non-pharma environments.

Together with educational and charitable organizations, transfusion facilities have ventured into the stem cell discipline, with the intention of testing of novel cell-based therapeutics in a scientific setting for future advertising and marketing approval. The truth that high quality administration constructions, that are required for compliance with good scientific follow rules, have been initially designed for product improvement in company environments represents a serious problem for a lot of builders. On this Commentary, challenges that non-pharmaceutical establishments should overcome to translate cell-based merchandise into scientific therapies can be mentioned from a high quality standpoint. Moreover, our improvement expertise for a mesenchymal stromal cell-based remedy can be shared as a case research.

Nanomedicine: a pharma perspective.

Nanotechnology as utilized to drugs is just not a brand new discipline. The primary nanomedicines accredited to be used have been developed from analysis relationship again to the 1970s. These liposomal formulations of current medication confirmed improved therapeutic exercise and decreased toxicity within the nonclinical mannequin methods. Nevertheless, these advantages proved extra refined and tougher to show in sufferers. This reality, mixed with the technical challenges in commercial-scale manufacturing of nanoparticles, led to solely restricted funding in nanomedicines by the key pharmaceutical corporations.

Even so, analysis on nanomedicines has proceeded apace in educational laboratories and smaller biopharmaceutical corporations. New supplies and drug mixtures have been studied, and concentrating on moieties added with the intention of enhancing the therapeutic index. Right now many of those new designs are in, or are approaching, scientific testing. It’ll take just one or two to achieve success to vary the best way pharmaceutical corporations view this discipline of revolutionary analysis.

Evaluation of (poly)phenols in grape (Vitis vinifera L.) stems through the use of meals/pharma business suitable solvents and Response Floor Methodology.

A Field-Behnken design of Response Floor Methodology (RSM) was carried out to analyse the impact of time (10-30 min), temperature (25-95°C), and solvents focus (5-90%) on the extraction of whole phenolics, flavonoids, ortho-diphenols, and anthocyanins in addition to to evaluate the ABTS(+) scavenging capability, which have been thought-about as response variables. Values coefficients of willpower (R(2)), starting from 0.903 to 0.996, fitted for describing environment friendly extraction of bioactive (poly)phenols and antioxidant exercise. The recorded knowledge allowed to ascertain the optimum extraction situations at 23.Zero min, 95.0°C, and 57.9% of food-quality ethanol/water for Vitis vinifera L. var.

Vornado™ miniature vortex mixer with red cup head, 100 to 240V with European 2 prong ADAPTER*
BV101-R-E	Benchmark Scientific	1 PC	EUR 224.6

MyBlock™ Mini Dry Bath, 100-240V (European 2 prong plug)
BSH200-E	Benchmark Scientific	1 PC	EUR 309.1

MyFuge™ 12 Mini Centrifuge 100-240V (European 2 prong plug)
C1012-E	Benchmark Scientific	1 PC	EUR 448.5

Incu-Mixer MP2™ Heated Plate Vortexer 115-240V European plug)
H6002-E	Benchmark Scientific	1 PC	EUR 1992.7

European Pesticide Mix 2017-170 100 ug/mL (100 ppm) 1mLin Acetonitrile.
EU-2017-170	Scientific Laboratory Supplies	1ML	EUR 78

MyBlock™ Mini dry bath with cooling, 100-240V (European 2 prong Plug)
BSH300-E	Benchmark Scientific	1 PC	EUR 817.6

MyBlock™ HL Mini Dry Bath with Heated Lid, 100-240V (European 2 prong plug)
BSH200-HL-E	Benchmark Scientific	1 PC	EUR 507.3

Orbi-Shaker™ Jr with rubber mat platform (9.5"x8"), 100-240V (European 2 prong plug)
BT302-E	Benchmark Scientific	1 PC	EUR 1182.1

MyFuge™ Mini Centrifuge, blue lid, with 2 rotors, 100-240V (European 2 prong plug)
C1008-B-E	Benchmark Scientific	1 PC	EUR 346.9

MyFuge™ Mini Centrifuge, clear lid, with 2 rotors, 100-240V (European 2 prong plug)
C1008-C-E	Benchmark Scientific	1 PC	EUR 346.9

MyFuge™ Mini Centrifuge, green lid, with 2 rotors, 100-240V (European 2 prong plug)
C1008-G-E	Benchmark Scientific	1 PC	EUR 346.9

EP Reagent Ruthenium Red Sol.
1075201	Scientific Laboratory Supplies	100ML	EUR 129.6

Vornado™ miniature vortexer, grey cup head, 100 to 240V with European 2 prong PLUG*
BV101-E	Benchmark Scientific	1 PC	EUR 224.6

BenchWaver™ 3D Rocker with flat mat, 13.5x13" platform, 100-240V (European 2 prong plug)
B3D5000-E	Benchmark Scientific	1 PC	EUR 1518.6

MyFuge™ Mini Centrifuge, purple lid, with 2 rotors, 100-240V (European 2 prong plug)
C1008-P-E	Benchmark Scientific	1 PC	EUR 346.9

EP Reagent Phenol Red Sol. R2
1063603	Scientific Laboratory Supplies	500ML	EUR 99.6

Congo Red
2588-100	Biovision	each	EUR 144

Congo Red
2588-500	Biovision	each	EUR 352.8

Congo red
CB0324	Bio Basic	50g	EUR 79.84

Congo Red
B7766-50	ApexBio	50 mg	EUR 154.8

Congo Red
HY-D0236	MedChemExpress	500mg	EUR 159.6

Orbi-Shaker™ MP with 4 position micro plate platform, 100-240V (European 2 prong plug)
BT1502-E	Benchmark Scientific	1 PC	EUR 1145.9

EP Reagent Methyl Red Mixed Sol.
1055101	Scientific Laboratory Supplies	100ML	EUR 52.8

Vornado™ miniature vortex mixer with blue cup head, 100 to 240V with European 2 prong ADAPTER*
BV101-B-E	Benchmark Scientific	1 PC	EUR 224.6

Vornado™ miniature vortex mixer with green cup head, 100 to 240V with European 2 prong ADAPTER*
BV101-G-E	Benchmark Scientific	1 PC	EUR 224.6

Vornado™ miniature vortex mixer with purple cup head, 100 to 240V with European 2 prong ADAPTER*
BV101-P-E	Benchmark Scientific	1 PC	EUR 224.6

EP Reagent Indicator Sol. Methyl Red 0.02%
1055102	Scientific Laboratory Supplies	100ML	EUR 52.8

CP Reagent Coloration Primary Solution Red
CPPR01	Scientific Laboratory Supplies	100ML	EUR 206.4

Congo Red Powder
abx090680-5g	Abbexa	5 g	EUR 226.8

Congo Red Solution
CRA030	ScyTek Laboratories	30 ml	EUR 88.8

Congo Red Solution
CRA500	ScyTek Laboratories	500 ml	EUR 127.2

Congo Red Solution
CRA999	ScyTek Laboratories	1000 ml	EUR 171.6

Congo Red (C.I. 22120)
GT5674-100G	Glentham Life Sciences	100 g	EUR 74.4

Congo Red (C.I. 22120)
GT5674-250G	Glentham Life Sciences	250 g	EUR 103.2

Congo Red (C.I. 22120)
GT5674-25G	Glentham Life Sciences	25 g	EUR 54

Congo Red (C.I. 22120)
GT5674-100	Glentham Life Sciences	100	EUR 31.7

Congo Red (C.I. 22120)
GT5674-25	Glentham Life Sciences	25	EUR 16.4

Congo Red (C.I. 22120)
GT5674-250	Glentham Life Sciences	250	EUR 55.4

EP Reagent Biuret Reagent
1011601	Scientific Laboratory Supplies	1L	EUR 52.8

EP Reagent Iodoplatinate Reagent
1046300	Scientific Laboratory Supplies	200ML	EUR 446.4

EP Reagent Molybdovanadic Reagent
1056700	Scientific Laboratory Supplies	100ML	EUR 52.8

EP Reagent Methoxyphenylacetic Reagent
1053601	Scientific Laboratory Supplies	100ML	EUR 435.6

Congo Red Indicator 0.1%
COR01001	Scientific Laboratory Supplies	1L	EUR 301.59

Congo Red Indicator 0.1%
COR01005	Scientific Laboratory Supplies	500ML	EUR 90.09

Congo Red Indicator 1%
COR1005	Scientific Laboratory Supplies	500ML	EUR 110.98

Congo Red Indicator 0.1%
COR105	Scientific Laboratory Supplies	500ML	EUR 90.09

EP Reagent Sulfomolybdic Reagent R3
1086500	Scientific Laboratory Supplies	1L	EUR 354

EP Reagent Phosphomolybdotungstic Reagent
1065000	Scientific Laboratory Supplies	100ML	EUR 201.6

EP Reagent Bromocresol Green Methyl Red Mixed Indicator
1012602	Scientific Laboratory Supplies	100ML	EUR 52.8

EP Reagent Bromocresol Green - Methyl Red Mixed Indicator
10126021	Scientific Laboratory Supplies	1L	EUR 263.73

EP Reagent Bromocresol Green - Methyl Red Mixed Indicator
10126025	Scientific Laboratory Supplies	5L	EUR 406.8

USP Sol. Congo Red TS
USP1901	Scientific Laboratory Supplies	100ML	EUR 71.81

USP Sol. Congo Red TS
USP1905	Scientific Laboratory Supplies	500ML	EUR 118.81

FD Congo Red Solution™
PS108	FD Neurotechnologies	500 ml	EUR 284.4

Congo Red "high purity grade"
80028	Biotium	100MG	EUR 206.4
Description: Minimum order quantity: 1 unit of 100MG

Amyloid Stain Kit (Congo Red)
AMY-1	ScyTek Laboratories	1 kit(s)	EUR 198

Amyloid Stain Kit (Congo Red)
AMY-2	ScyTek Laboratories	1 kit(s)	EUR 130.8

BOP reagent
5-02141	CHI Scientific	25g	Ask for price

BOP reagent
5-02142	CHI Scientific	100g	Ask for price

MTS Reagent
2808-1000	Biovision	each	EUR 1188

MTS Reagent
2808-250	Biovision	each	EUR 438

MTT Reagent
2809-1G	Biovision	each	EUR 216

MTT Reagent
2809-5G	Biovision	each	EUR 652.8

BOP reagent
A7015-100000	ApexBio	100 g	EUR 240
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

BOP reagent
A7015-25000	ApexBio	25 g	EUR 135.6
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Traut's Reagent
2330-1000	Biovision	each	EUR 418.8

Traut's Reagent
2330-500	Biovision	each	EUR 248.4

VeZol Reagent
R411-01	Vazyme	100 ml	EUR 76.4

VeZol Reagent
R411-02	Vazyme	200 ml	EUR 127.6

Bluing Reagent
BRT030	ScyTek Laboratories	30 ml	EUR 72

Bluing Reagent
BRT125	ScyTek Laboratories	125 ml	EUR 75.6

Bluing Reagent
BRT3800	ScyTek Laboratories	1 Gal.	EUR 220.8

Bluing Reagent
BRT500	ScyTek Laboratories	500 ml	EUR 91.2

Bluing Reagent
BRT999	ScyTek Laboratories	1000 ml	EUR 105.6

BURGESS REAGENT
702010	Survival Technologies	each	Ask for price

Chymase reagent
30C-CP1129	Fitzgerald	5 units	EUR 2622
Description: Purified native Human Chymase reagent

Nessler Reagent
NESSR	Scientific Laboratory Supplies	500ML	EUR 182.4

FreeZol Reagent
R711-01	Vazyme	100 ml	EUR 71.2

FreeZol Reagent
R711-02	Vazyme	200 ml	EUR 127.2

Chromium Reagent
1206699	Scientific Laboratory Supplies	EACH	EUR 157.2

Bradford reagent
BDE641	Bio Basic	100ml	EUR 73.21

Beaucage reagent
HY-100951	MedChemExpress	10mM/1mL	EUR 151.2

Bradford Reagent
GT1202-1	Glentham Life Sciences	1	EUR 165.7

Bradford Reagent
GT1202-500	Glentham Life Sciences	500	EUR 105.5

Cod Reagent 0-15000Ppm
24159-51	Scientific Laboratory Supplies	PK25	EUR 116.4

Phosphate Reagent
106199	Scientific Laboratory Supplies	PK100	EUR 69.6

Ninhydrin Reagent
MIC6746	Scientific Laboratory Supplies	EACH	EUR 31.12

Detection Reagent Concentrate, 1ML
X041-1ML	Arbor Assays	1ML	EUR 109

COD Reagent (1977 method)
WTR50W	Scientific Laboratory Supplies	2.5L	EUR 135.6

Convoy? Transfection Reagent
1110-1ml	ACTGene	each	EUR 409.2

DTPA Extraction Reagent Concentrate
DTPAE01	Scientific Laboratory Supplies	1L	EUR 434.4

ECL Start Reagent 2000cm2
RPN3243	Scientific Laboratory Supplies	EACH	EUR 138

ECL Start Reagent 4000cm2
RPN3244	Scientific Laboratory Supplies	EACH	EUR 222

BCA Reagent, 16ML
C144-16ML	Arbor Assays	16ML	EUR 132

TDA Reagent - 10mL
MIC6732	Scientific Laboratory Supplies	EACH	EUR 26.33

PYR Reagent - 10mL
MIC6744	Scientific Laboratory Supplies	EACH	EUR 31.12

Olsens Extraction Reagent Concentrate
OLSER01	Scientific Laboratory Supplies	1L	EUR 91.2

Thioacetamide Reagent
THIOR01	Scientific Laboratory Supplies	100ML	EUR 99.6

Silica 3 Reagent
27169	Scientific Laboratory Supplies	100ML	EUR 99.6

BSA (Reagent Grade)
30-AB79	Fitzgerald	1 kg	EUR 1862.4
Description: Reagent Grade Bovine Serum Albumin (99% pure)

BSA (Reagent Grade)
30-AB81	Fitzgerald	200 grams	EUR 571.2
Description: Reagent Grade Sulphydryl Blocked BSA (99% pure)

Girard's reagent T
20-abx184099	Abbexa	EUR 243.60 EUR 376.80	100 g 500 g

Tri-RNA Reagent
FATRR-001	Favorgen	100ml	EUR 283.2

Tri-RNA Reagent
FATRR-002	Favorgen	50ml	EUR 211.2

Tri-RNA Reagent
FATRR-003	Favorgen	450ml	EUR 774

Schiff''s reagent
GT3929-1	Glentham Life Sciences	1	EUR 113.1

Schiff''s reagent
GT3929-250	Glentham Life Sciences	250	EUR 37.7

ECL Start Reagent 200cm2
RPN3245	Scientific Laboratory Supplies	EACH	EUR 26.4

Biotin reagent (HRP)
65C-CE0202	Fitzgerald	5 mg	EUR 292.8
Description: HRP conjugated biotin labelling reagent

EP Reagent Ferroin
1038100	Scientific Laboratory Supplies	100ML	EUR 96

Griess Reagent Kit
30100	Biotium	1KIT	EUR 178.8
Description: Minimum order quantity: 1 unit of 1KIT

Alcohol, Reagent (70%)
EAS500	ScyTek Laboratories	500 ml	EUR 94.8

Alcohol, Reagent (70%)
EAS999	ScyTek Laboratories	1000 ml	EUR 121.2

Citric Acid Reagent
2254232	Scientific Laboratory Supplies	EACH	EUR 52.8

SulfaVer 4 Reagent
2106769	Scientific Laboratory Supplies	PK100	EUR 78

DTT (Cleland's reagent)
DB0058	Bio Basic	5g	EUR 101.76

DTNB (Ellman's Reagent)
DB0113	Bio Basic	5g	EUR 117.42

n-Heptane Reagent
HC5400	Bio Basic	1L	EUR 94.8

Bottle Reagent 500ml Pyrex
B54564	Scientific Laboratory Supplies	PK10	EUR 124.8

Bradford Dye Reagent
0209R	AthenaES	100 ml	EUR 157.2

DeStreak reagent 1mL
17600318	Scientific Laboratory Supplies	EACH	EUR 82.8

FcR blocking Reagent
20-abx290024	Abbexa	EUR 452.40 EUR 619.20	200 tests 400 tests

Detection Reagent A
abx296004-120ul	Abbexa	120 ul	EUR 385.2

Olsens Mixed Reagent
OLSMR01	Scientific Laboratory Supplies	1L	EUR 168

EZ Cap? Reagent AG
B8176-.01	ApexBio	10 µl (100 mM)	EUR 369.6
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.05	ApexBio	50 µl (100 mM)	EUR 1488
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.1	ApexBio	100 µl (100 mM)	EUR 2656.8
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent GG
B8177-.01	ApexBio	10 µl (100 mM)	EUR 369.6
Description: EZ Cap Reagent GG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA resulting in a Cap 1 structure. EZ Cap GG requires a GG initiator. EZ Cap GG typically provides >90% capped material generating a natural Cap 1 structure.

EZ Cap? Reagent GG
B8177-.05	ApexBio	50 µl (100 mM)	EUR 1488
Description: EZ Cap Reagent GG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA resulting in a Cap 1 structure. EZ Cap GG requires a GG initiator. EZ Cap GG typically provides >90% capped material generating a natural Cap 1 structure.

Bray P1 Extracting Reagent Concentrate
BRAY01	Scientific Laboratory Supplies	1L	EUR 76.8

Bottle Reagent 1000 ml Pyrex
BOT5356	Scientific Laboratory Supplies	PK10	EUR 177.6

HAMA blocking reagent
85R-1001	Fitzgerald	1 gram	EUR 2368.8
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1001P	Fitzgerald	1 gram	EUR 2628
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1003	Fitzgerald	1 gram	EUR 2368.8
Description: HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

HAMA blocking reagent
85R-1014	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in assays specific for clinical false positive samples

HAMA blocking reagent
85R-1025	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in immunoassays

HAMA blocking reagent
85R-1026	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in immunoassays

Ethyl acetate Reagent
EC4600	Bio Basic	1L	EUR 94.8

Hanna Bromine Reagent
WAT1535	Scientific Laboratory Supplies	EACH	EUR 39.6

Hanna Nitrate Reagent
WAT1547	Scientific Laboratory Supplies	EACH	EUR 111.6

Johnson Litmus Red Paper
PAP1130	Scientific Laboratory Supplies	PK10	EUR 9.6

Reagent Reservoir 50ml
F267670	Scientific Laboratory Supplies	PK100	EUR 262.8

Oxidase Strip Containing Reagent
MIC6738	Scientific Laboratory Supplies	EACH	EUR 43.09

FRAP Reagent A, 1.4ML
C148-1.4ML	Arbor Assays	1.4ML	EUR 150

FRAP Reagent B, 1.4ML
C149-1.4ML	Arbor Assays	1.4ML	EUR 150

EL Transfection Reagent
20-abx098880	Abbexa	EUR 460.80 EUR 644.40	0.75 ml 1.5 ml

Ammonia Monitor Reagent
ROREA10	Scientific Laboratory Supplies	10L	EUR 253.29

Color Reagent A, 5ML
X092-5ML	Arbor Assays	5ML	EUR 48

Color Reagent B, 5ML
X093-5ML	Arbor Assays	5ML	EUR 48

Catalase Reagent Dropper
261203	Scientific Laboratory Supplies	PK50	EUR 88.78

Sample Transport Reagent
SSFIN-0007	Zeptometrix	20mL	EUR 32

TissueDigest Reagent, 20X
T101	Insitus Biotechnologies	10ml	EUR 252

Dissociation Reagent, 1ML
X017-1ML	Arbor Assays	1ML	EUR 48

Dissociation Reagent, 5ML
X017-5ML	Arbor Assays	5ML	EUR 59

Dissociation Reagent, 1ML
X058-1ML	Arbor Assays	1ML	EUR 19

Dissociation Reagent, 5ML
X058-5ML	Arbor Assays	5ML	EUR 48

Dissociation Reagent, 1ML
X154-1ML	Arbor Assays	1ML	EUR 48

Dissociation Reagent, 5ML
X154-5ML	Arbor Assays	5ML	EUR 59

Ohira-Bestmann Reagent
GW0498-1	Glentham Life Sciences	1	EUR 300.9

Ohira-Bestmann Reagent
GW0498-5	Glentham Life Sciences	5	EUR 1089.4

EP Reagent Starch Sol.
1085103	Scientific Laboratory Supplies	100ML	EUR 63.6

EP Reagent 0.05M Iodine
R3002700	Scientific Laboratory Supplies	1L	EUR 78

EP Reagent 0.01M Iodine
R3002900	Scientific Laboratory Supplies	1L	EUR 150

Color Reagent A, 15ML
X094-15ML	Arbor Assays	15ML	EUR 59

Color Reagent A, 38ML
X094-38ML	Arbor Assays	38ML	EUR 120

Color Reagent B, 15ML
X095-15ML	Arbor Assays	15ML	EUR 59

Color Reagent B, 38ML
X095-38ML	Arbor Assays	38ML	EUR 120

Potassium Dichromate Reagent 0.267N
KCR267F	Scientific Laboratory Supplies	1L	EUR 70.8

LP4K Transfection Reagent
LP4K	GenTarget	1.0 ml / vial	EUR 364.8
Description: Lipid based transfection reagent for large plasmid and multiple plasmid transfection in both adhesive and suspenstion cell types.

Dissociation Reagent, 25ML
X017-25ML	Arbor Assays	25ML	EUR 242

Hanna Phosphorous Reagent
WAT1513	Scientific Laboratory Supplies	PK100	EUR 49.2

Palintest Reagent Nitrate
WAT8098	Scientific Laboratory Supplies	PK200	EUR 176.4

20% Citric Acid Reagent
CA20WV25	Scientific Laboratory Supplies	25L	EUR 1035.34

20% Citric Acid Reagent
CA20WVF	Scientific Laboratory Supplies	1L	EUR 120

One Step-RNA Reagent
BS409A	Bio Basic	25ml	EUR 82.84

One Step-RNA Reagent
BS410A	Bio Basic	100ml	EUR 133.08

Annexin V-PE Reagent
1014-1000	Biovision	each	EUR 1358.4

Annexin V-PE Reagent
1014-200	Biovision	each	EUR 483.6

EP Reagent 0.001M Silver Nitrate
3009300	Scientific Laboratory Supplies	1L	EUR 206.4

BODIPY-Acetylene Reagent
2594-1	Biovision	each	EUR 248.4

BODIPY-Acetylene Reagent
2594-5	Biovision	each	EUR 810

Folin-Ciocalteus Reagent
FOCIRE01	Scientific Laboratory Supplies	100ML	EUR 118.8

Cytotoxicity Control Reagent (Saponin)
CTTX-050	BioAssay Systems	(50mg)	EUR 109
Description: Useful as a cytotoxic control agent in the CQBL-05K and CQMT-500 Cell Viability Assay Kits. IC50 = 0.002 wt%. Shelf life:12 months.

Biotin reagent (Alk Phos)
65C-CE0201	Fitzgerald	1 mg	EUR 253.2
Description: Alkaline Phosphatase conjugated biotin labelling reagent

Aluminum I Reagent Kit
515460BT	Scientific Laboratory Supplies	PK100	EUR 25.2

Simax Reagent Bottle 1L
BOT53100	Scientific Laboratory Supplies	PK10	EUR 66

Simax Reagent Bottle 2L
BOT53120	Scientific Laboratory Supplies	PK10	EUR 135.6

Simax Reagent Bottle 5L
BOT5314	Scientific Laboratory Supplies	EACH	EUR 110.4

Reagent Bottle Amber 1L
BOT64302	Scientific Laboratory Supplies	PK10	EUR 206.4

Reagent Bottle Amber 2L
BOT64320	Scientific Laboratory Supplies	PK6	EUR 121.2

Annexin V-Cy5 Reagent
1013-1000	Biovision	each	EUR 1358.4

Annexin V-Cy5 Reagent
1013-200	Biovision	each	EUR 483.6

Annexin V-Cy3 Reagent
1002-1000	Biovision	each	EUR 1358.4

Annexin V-Cy3 Reagent
1002-200	Biovision	each	EUR 483.6

Reagent reservoir 50 mL
DD53482	Scientific Laboratory Supplies	PK100	EUR 230.4

50 ml Reagent Reservoir
GR238016	Genorise Scientific	Pack of 200	EUR 148

Nitrate Reagent A - 10mL
MIC6720	Scientific Laboratory Supplies	EACH	EUR 26.33

Nitrate Reagent B- 10mL
MIC6722	Scientific Laboratory Supplies	EACH	EUR 26.33

EP Reagent Ref Sol. Y2
EPY201A	Scientific Laboratory Supplies	2ML	EUR 124.03

‘Viosinho’ (white selection), and 23.four min, 84.2°C, and 63.8% for var. ‘Touriga Nacional’ (pink selection). The achievement of optimum extraction situations of phenolics from grape stems utilizing solvents suitable with additional makes use of in meals/pharma industries demonstrated that RSM constitutes a robust device for deriving optimum situations for extraction of antioxidant phenolic compounds from grape stems.