Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline.

Schistosomiasis, certainly one of 17 illnesses deemed to be uncared for by the World Well being Group, has acquired little consideration from the biopharmaceutical business. As a result of this, solely a handful of medication have been developed to deal with schistosomiasis, with just one, praziquantel, utilized in most endemic areas. Rising concern over resistance coupled with praziquantel’s incomplete efficacy throughout all phases of the Schistosoma platyhelminth life cycle highlights the pressing want for brand spanking new medication.

The WIPO Re:Search consortium is a platform whereupon biopharmaceutical firm compounds are being repurposed to effectively and cost-effectively develop new medication for uncared for illnesses resembling schistosomiasis. This text summarizes latest clinical-stage efforts to determine new antischistosomals and highlights biopharmaceutical firm compounds with potential for repurposing to deal with schistosomiasis.

Flavonoids on the pharma-nutrition interface: Is a therapeutic index in demand?

The consumption of flavonoid-rich meals may have useful results on well being. Nevertheless, totally different lessons of flavonoids have totally different impact on illness threat and the connection between flavonoid consumption and threat of illness seemed to be non-linear. Moreover, contrarily to nutritional vitamins, there aren’t any signs of deficiency for flavonoids; due to this fact, our physique treats them like different xenobiotics. Due to this fact, a therapeutic index must be decided. Regardless of flavonoids are on the pharma-nutrition interface, medication and meals are topic to totally different regulatory frameworks and there’s no really helpful each day allowance (RDA) for flavonoids.

Comparatively little is understood in regards to the efficacy, security and underlying mechanisms of those bioactive compounds, particularly when taken in live performance with medication. Flavonoids may act each as medication and pro-drugs with pharmacological and toxicological promiscuity. As a result of low bioavailability, the gastrointestinal tract may very well be the first goal of flavonoids and metabolites. Completely different results have been noticed after acute and power consumption and bioavailability and bioactivity have excessive inter-individual variability.

Moreover, the difficulties within the design and within the interpretation of human intervention research make troublesome the institution of a therapeutic index for flavonoids. Most likely the idea of ‘personalised diet’ beforehand proposed may very well be the higher strategy. Nevertheless, regardless of extra research are wanted with the intention to set up a therapeutic index for every flavonoid subclasses, for the time being RDA of whole flavonoids may very well be between 250-400 mg/d, respecting the seasonality of meals sources.

High quality compliance within the shift from cell transplantation to cell remedy in non-pharma environments.

Together with educational and charitable organizations, transfusion facilities have ventured into the stem cell discipline, with the intention of testing of novel cell-based therapeutics in a scientific setting for future advertising and marketing approval. The truth that high quality administration constructions, that are required for compliance with good scientific follow rules, have been initially designed for product improvement in company environments represents a serious problem for a lot of builders. On this Commentary, challenges that non-pharmaceutical establishments should overcome to translate cell-based merchandise into scientific therapies can be mentioned from a high quality standpoint. Moreover, our improvement expertise for a mesenchymal stromal cell-based remedy can be shared as a case research.

Nanomedicine: a pharma perspective.

Nanotechnology as utilized to drugs is just not a brand new discipline. The primary nanomedicines accredited to be used have been developed from analysis relationship again to the 1970s. These liposomal formulations of current medication confirmed improved therapeutic exercise and decreased toxicity within the nonclinical mannequin methods. Nevertheless, these advantages proved extra refined and tougher to show in sufferers. This reality, mixed with the technical challenges in commercial-scale manufacturing of nanoparticles, led to solely restricted funding in nanomedicines by the key pharmaceutical corporations.

Even so, analysis on nanomedicines has proceeded apace in educational laboratories and smaller biopharmaceutical corporations. New supplies and drug mixtures have been studied, and concentrating on moieties added with the intention of enhancing the therapeutic index. Right now many of those new designs are in, or are approaching, scientific testing. It’ll take just one or two to achieve success to vary the best way pharmaceutical corporations view this discipline of revolutionary analysis.

Evaluation of (poly)phenols in grape (Vitis vinifera L.) stems through the use of meals/pharma business suitable solvents and Response Floor Methodology.

A Field-Behnken design of Response Floor Methodology (RSM) was carried out to analyse the impact of time (10-30 min), temperature (25-95°C), and solvents focus (5-90%) on the extraction of whole phenolics, flavonoids, ortho-diphenols, and anthocyanins in addition to to evaluate the ABTS(+) scavenging capability, which have been thought-about as response variables. Values coefficients of willpower (R(2)), starting from 0.903 to 0.996, fitted for describing environment friendly extraction of bioactive (poly)phenols and antioxidant exercise. The recorded knowledge allowed to ascertain the optimum extraction situations at 23.Zero min, 95.0°C, and 57.9% of food-quality ethanol/water for Vitis vinifera L. var.

Congo Red
HY-D0236	MedChemExpress	500mg	EUR 133

Congo red
CB0324	Bio Basic	50g	EUR 66.53
Product category: Biochemicals/Indicators/Stains/Biological Stains

Congo Red Powder
abx090680-5g	Abbexa	5 g	EUR 189
Shipped within 5-10 working days.

Congo Red Solution
CRA030	ScyTek Laboratories	30 ml	EUR 74

Congo Red Solution
CRA500	ScyTek Laboratories	500 ml	EUR 106

Congo Red Solution
CRA999	ScyTek Laboratories	1000 ml	EUR 143

Congo Red (C.I. 22120)
GT5674-100G	Glentham Life Sciences	100 g	EUR 62

Congo Red (C.I. 22120)
GT5674-250G	Glentham Life Sciences	250 g	EUR 86

Congo Red (C.I. 22120)
GT5674-25G	Glentham Life Sciences	25 g	EUR 45

Amyloid Stain Kit (Congo Red)
AMY-1	ScyTek Laboratories	1 kit(s)	EUR 165

Amyloid Stain Kit (Congo Red)
AMY-2	ScyTek Laboratories	1 kit(s)	EUR 109

Congo Red "high purity grade"
80028	Biotium	100MG	EUR 172
Description: Minimum order quantity: 1 unit of 100MG

FD Congo Red Solution™
PS108	FD Neurotechnologies	500 ml	EUR 229.05
Description: Best quality products

Congo Red *UltraPure grade* *CAS 573-58-0*
23056	AAT Bioquest	100 mg	EUR 115
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

UPP-110HG Print paper
2140913	Atto	1unit	EUR 356

Paper 2.25"x50 feet
B4000-PA	BenchMark	1 PC	EUR 342.53
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

thermal paper 112mm/25m
AM112	Consort	ea	EUR 24

Blotting Paper, 10X15cm, 100 Sheets
PP3322	Bio Basic	1PK, 100UNIT	EUR 105.68
Product category: Electrophoresis Related/Blotting Papers

Blotting Paper, 15X15cm, 100 Sheets
PP3323	Bio Basic	1PK, 100UNIT	EUR 117.04
Product category: Electrophoresis Related/Blotting Papers

Blotting Paper, 20X20cm, 100 Sheets
PP3324	Bio Basic	1PK, 100UNIT	EUR 166.4
Product category: Electrophoresis Related/Blotting Papers

Weighing Paper, 3X3, 200Sheets/Bag
WT111	Bio Basic	1PK, 200UNIT	EUR 57.29
Product category: Labware/Lab Supplies/Weighing Paper

Weighing Paper, 4X4, 100Sheets/Bag
WT112	Bio Basic	1PK, 100UNIT	EUR 57.83
Product category: Labware/Lab Supplies/Weighing Paper

Weighing Paper, 6X6, 100Sheets/Bag
WT113	Bio Basic	1PK, 100UNIT	EUR 60.44
Product category: Labware/Lab Supplies/Weighing Paper

Chymase reagent
30C-CP1129	Fitzgerald	5 units	EUR 2185
Description: Purified native Human Chymase reagent

Traut's Reagent
2330-1000	Biovision		EUR 349

Traut's Reagent
2330-500	Biovision		EUR 207

MTS Reagent
2808-1000	Biovision		EUR 990

MTS Reagent
2808-250	Biovision		EUR 365

MTT Reagent
2809-1G	Biovision		EUR 180

MTT Reagent
2809-5G	Biovision		EUR 544

BOP reagent
5-02141	CHI Scientific	25g	Ask for price

BOP reagent
5-02142	CHI Scientific	100g	Ask for price

Bluing Reagent
BRT030	ScyTek Laboratories	30 ml	EUR 60

Bluing Reagent
BRT125	ScyTek Laboratories	125 ml	EUR 63

Bluing Reagent
BRT3800	ScyTek Laboratories	1 Gal.	EUR 184

Bluing Reagent
BRT500	ScyTek Laboratories	500 ml	EUR 76

Bluing Reagent
BRT999	ScyTek Laboratories	1000 ml	EUR 88

BOP reagent
A7015-100000	ApexBio	100 g	EUR 200
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

BOP reagent
A7015-25000	ApexBio	25 g	EUR 113
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Beaucage reagent
HY-100951	MedChemExpress	10mM/1mL	EUR 126

Bradford reagent
BDE641	Bio Basic	100ml	EUR 61.01
Product category: Biochemicals/Biology Reagents/Protein Related

BSA (Reagent Grade)
30-AB79	Fitzgerald	1 kg	EUR 1552
Description: Reagent Grade Bovine Serum Albumin (99% pure)

BSA (Reagent Grade)
30-AB81	Fitzgerald	200 grams	EUR 476
Description: Reagent Grade Sulphydryl Blocked BSA (99% pure)

Griess Reagent Kit
30100	Biotium	1KIT	EUR 149
Description: Minimum order quantity: 1 unit of 1KIT

BODIPY-Acetylene Reagent
2594-1	Biovision		EUR 207

BODIPY-Acetylene Reagent
2594-5	Biovision		EUR 675

Biotin reagent (HRP)
65C-CE0202	Fitzgerald	5 mg	EUR 244
Description: HRP conjugated biotin labelling reagent

Convoy? Transfection Reagent
1110-1ml	ACTGene		EUR 341

Bradford Dye Reagent
0209R	AthenaES	100 ml	EUR 131

HAMA blocking reagent
85R-1001	Fitzgerald	1 gram	EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1001P	Fitzgerald	1 gram	EUR 2190
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1003	Fitzgerald	1 gram	EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

HAMA blocking reagent
85R-1014	Fitzgerald	50 mg	EUR 192
Description: HAMA blocking reagent for use in assays specific for clinical false positive samples

HAMA blocking reagent
85R-1025	Fitzgerald	50 mg	EUR 192
Description: HAMA blocking reagent for use in immunoassays

HAMA blocking reagent
85R-1026	Fitzgerald	50 mg	EUR 192
Description: HAMA blocking reagent for use in immunoassays

Girard's reagent T
20-abx184099	Abbexa	EUR 203.00 EUR 314.00	100 g 500 g
Shipped within 1-2 weeks.

EL Transfection Reagent
20-abx098880	Abbexa	EUR 384.00 EUR 537.00	0.75 ml 1.5 ml
Shipped within 5-10 working days.

Mycoplasma Prevention Reagent
20-abx098886	Abbexa	EUR 425.00 EUR 509.00	1 ml 5 ml
Shipped within 5-10 working days.

Alcohol, Reagent (70%)
EAS500	ScyTek Laboratories	500 ml	EUR 79

Alcohol, Reagent (70%)
EAS999	ScyTek Laboratories	1000 ml	EUR 101

BCA Reagent, 16ML
C144-16ML	Arbor Assays	16ML	EUR 163

Biolipidure-1002-Reagent
Biolipidure-1002-10	Cusabio	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1002-Reagent
Biolipidure-1002-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-10	Biolipidure	10mL	EUR 196
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-100	Biolipidure	100mL	EUR 1223
Biolipidure enhances sensitivity and accuracy. Biolipidure suppresses non-specific adsorption. Biolipidure stabilizes antibodies and enzymes. Biolipidure eliminates lot-to-lot variations. Biolipidure does not require biohazardous handling.
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

FcR blocking Reagent
20-abx290024	Abbexa	EUR 377.00 EUR 516.00	200 tests 400 tests
Shipped within 2-3 weeks.

Detection Reagent A
abx296004-120ul	Abbexa	120 ul	EUR 321
Shipped within 5-10 working days.

Mycoplasma Prevention Reagent
20-abx298005	Abbexa	EUR 203.00 EUR 286.00	1 ml 5 ml
Shipped within 5-10 working days.

PhosphoBlocker Blocking Reagent
AKR-103	Cell Biolabs	1L	EUR 328
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

PhosphoBlocker Blocking Reagent
AKR-104	Cell Biolabs	4L	EUR 711
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

Tri-RNA Reagent
FATRR-001	Favorgen	100ml	EUR 236

Tri-RNA Reagent
FATRR-002	Favorgen	50ml	EUR 176

Tri-RNA Reagent
FATRR-003	Favorgen	450ml	EUR 645

LP4K Transfection Reagent
LP4K	GenTarget	1.0 ml / vial	EUR 304
Description: Lipid based transfection reagent for large plasmid and multiple plasmid transfection in both adhesive and suspenstion cell types.

PureFection Transfection Reagent
LV750A-1	SBI	1 ml	EUR 359
Category: Lentiviral Technology

HighGene transfection reagent
RM09014	Abclonal	1000μl	EUR 270

TissueDigest Reagent, 20X
T101	Insitus Biotechnologies	10ml	EUR 210

ExFect2000 Transfection Reagent
T202-01	Vazyme	0.5 ml	EUR 227

ExFect2000 Transfection Reagent
T202-02	Vazyme	1 ml	EUR 316

ExFect2000 Transfection Reagent
T202-03	Vazyme	5 ml	EUR 1052

Dissociation Reagent, 1ML
X017-1ML	Arbor Assays	1ML	EUR 109

Dissociation Reagent, 25ML
X017-25ML	Arbor Assays	25ML	EUR 258

Dissociation Reagent, 5ML
X017-5ML	Arbor Assays	5ML	EUR 122

Dissociation Reagent, 1ML
X058-1ML	Arbor Assays	1ML	EUR 73

Dissociation Reagent, 5ML
X058-5ML	Arbor Assays	5ML	EUR 109

DTT (Cleland's reagent)
DB0058	Bio Basic	5g	EUR 84.8
Product category: Electrophoresis Related/Reducing Agents

DTNB (Ellman's Reagent)
DB0113	Bio Basic	5g	EUR 97.85
Product category: Biochemicals/Indicators/Stains/Peptide/Protein Related

Ethyl acetate Reagent
EC4600	Bio Basic	1L	EUR 79
Product category: Biochemicals/Solvents

n-Heptane Reagent
HC5400	Bio Basic	1L	EUR 79
Product category: Biochemicals/Solvents

Printer paper for AB-2270, 10/pk
3511065	Atto	2unit	EUR 363

Extra paper rolls for MR9600-TP printer
MR9600-PA	BenchMark	1 PC	EUR 86.75
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

RED antibody
22518-100ul	SAB	100ul	EUR 390

Ruthenium Red
2490-100	Biovision		EUR 131

Ruthenium Red
2490-500	Biovision		EUR 370

RED antibody
70R-13184	Fitzgerald	100 ul	EUR 457
Description: Affinity purified Rabbit polyclonal RED antibody

Nile Red
60029	Biotium	10MG	EUR 125
Description: Minimum order quantity: 1 unit of 10MG

RED Antibody
DF4352	Affbiotech	200ul	EUR 304
Description: RED Antibody detects endogenous levels of total RED.

RED Antibody
20-abx249463	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg
Shipped within 5-10 working days.

Ruthenium Red
B6740-100	ApexBio	100 mg	EUR 171

Nile Red
B8209-10	ApexBio	10 mg	EUR 108

Nile Red
B8209-100	ApexBio	100 mg	EUR 142

Nile Red
B8209-50	ApexBio	50 mg	EUR 125

Nile Red
B8209-500	ApexBio	500 mg	EUR 212

RED Antibody
ABD4352	Lifescience Market	100 ug	EUR 438

Tetrazolium Red
HY-D0714	MedChemExpress	500mg	EUR 108

Nile Red
HY-D0718	MedChemExpress	50mg	EUR 124

Trypan red
HY-D0983	MedChemExpress	5mg	EUR 533

Nile Red
GT2331-1G	Glentham Life Sciences	1 g	EUR 174

Nile Red
GT2331-250MG	Glentham Life Sciences	250 mg	EUR 87

Chlorophenol Red
GT3722-10G	Glentham Life Sciences	10 g	EUR 78

Chlorophenol Red
GT3722-25G	Glentham Life Sciences	25 g	EUR 126

Chlorophenol Red
GT3722-50G	Glentham Life Sciences	50 g	EUR 198

Chlorophenol Red
GT3722-5G	Glentham Life Sciences	5 g	EUR 59

Pyrogallol Red
GT7202-10G	Glentham Life Sciences	10 g	EUR 158

Pyrogallol Red
GT7202-1G	Glentham Life Sciences	1 g	EUR 54

Pyrogallol Red
GT7202-5G	Glentham Life Sciences	5 g	EUR 110

Bromophenol Red
GT7578-10G	Glentham Life Sciences	10 g	EUR 142

Bromophenol Red
GT7578-1G	Glentham Life Sciences	1 g	EUR 61

Bromophenol Red
GT7578-25G	Glentham Life Sciences	25 g	EUR 253

Bromophenol Red
GT7578-5G	Glentham Life Sciences	5 g	EUR 94

Quinaldine Red
GT7977-25G	Glentham Life Sciences	25 g	EUR 142

Quinaldine Red
GT7977-5G	Glentham Life Sciences	5 g	EUR 62

Phenol Red
GT9844-100G	Glentham Life Sciences	100 g	EUR 110

Phenol Red
GT9844-250G	Glentham Life Sciences	250 g	EUR 181

Phenol Red
GT9844-25G	Glentham Life Sciences	25 g	EUR 62

Phenol Red
GT9844-5G	Glentham Life Sciences	5 g	EUR 46

Neutral Red
G035	ABM	5 x 1.0ml	EUR 125

Cresol Red
GT0793-100G	Glentham Life Sciences	100 g	EUR 78

Cresol Red
GT0793-25G	Glentham Life Sciences	25 g	EUR 43

Methyl red
MB0627	Bio Basic	25g	EUR 61.31
Product category: Culture Media/Indicators/Stains

Neutral red
NB0652	Bio Basic	25g	EUR 65.66
Product category: Biochemicals/Indicators/Stains/Biological Stains

Phenol red
PB0420	Bio Basic	25g	EUR 70.88
Product category: Culture Media/Indicators/Stains

Crimean-Congo hemorrhagic fever virus Nucleoprotein (N)
1-CSB-EP328701CSB	Cusabio	EUR 611.00 EUR 309.00 EUR 1827.00 EUR 939.00 EUR 1218.00 EUR 397.00	100ug 10ug 1MG 200ug 500ug 50ug
MW: 68 kDa Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Crimean-Congo hemorrhagic fever virus Nucleoprotein(N) expressed in E.coli

Crimean-Congo hemorrhagic fever virus PCR kit
PCR-VH060-48R	Bioingentech	50T	EUR 524.4
Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Crimean-Congo hemorrhagic fever virus

Crimean-Congo hemorrhagic fever virus PCR kit
PCR-VH060-96R	Bioingentech	100T	EUR 669.4
Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Crimean-Congo hemorrhagic fever virus

DIRECTPCR LYSIS REAGENT (CELL)
302-C	Viagen	100 ml	EUR 207
Description: For use with cultured cells

Mouse IgG Blocking Reagent
30R-AH071	Fitzgerald	20 mg	EUR 258
Description: Mouse IgG (H + L) Blocking Reagent

DIRECTPCR LYSIS REAGENT (CELL)
301-C	Viagen	50 ml	EUR 141
Description: For use with cultured cells

MESG *Phosphate assay reagent*
21600	AAT Bioquest	5 mg	EUR 115
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Biotin reagent (Alk Phos)
65C-CE0201	Fitzgerald	1 mg	EUR 211
Description: Alkaline Phosphatase conjugated biotin labelling reagent

Biotin reagent (Glucose Oxidase)
65C-CE0203	Fitzgerald	5 mg	EUR 232
Description: Glucose Oxidase conjugated biotin labelling reagent

Annexin V-Cy5 Reagent
1013-1000	Biovision		EUR 1132

Annexin V-Cy5 Reagent
1013-200	Biovision		EUR 403

Annexin V-PE Reagent
1014-1000	Biovision		EUR 1132

Annexin V-PE Reagent
1014-200	Biovision		EUR 403

DIRECTPCR LYSIS REAGENT (TAIL)
102-T	Viagen	100ml	EUR 207
Description: Up to 500 tails (50ml)

REAGENT BOTTLE, 1L, PP
1500P-1L	CORNING	10/pk	EUR 100
Description: Reusable Plastics; Resusable Bottles

Annexin V-FITC Reagent
1001-1000	Biovision		EUR 1246

Annexin V-FITC Reagent
1001-200	Biovision		EUR 441

Annexin V-Cy3 Reagent
1002-1000	Biovision		EUR 1132

Annexin V-Cy3 Reagent
1002-200	Biovision		EUR 403

Annexin V-Biotin Reagent
1003-100	Biovision		EUR 370

Annexin V-Biotin Reagent
1003-1000	Biovision		EUR 2388

Annexin V-EGFP Reagent
1004-1000	Biovision		EUR 1132

Annexin V-EGFP Reagent
1004-200	Biovision		EUR 403

DIRECTPCR LYSIS REAGENT (TAIL)
101-T	Viagen	50 ml	EUR 141
Description: Up to 250 tails (50ml)

DIRECTPCR LYSIS REAGENT (EAR)
401-E	Viagen	25 ml	EUR 141
Description: For use with ear pieces

DIRECTPCR LYSIS REAGENT (EAR)
402-E	Viagen	50 ml	EUR 207
Description: For use with ear pieces

Cytotoxicity Control Reagent (Saponin)
CTTX-050	BioAssay Systems	(50mg)	EUR 135
Description: To be used as a cytotoxic control agent in the CellQuanti-BlueTM and CellQuanti-MTTTM Cell Viability Assay Kits. IC50 = 0.002 wt%. Kit size: (50mg) tests. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Chicken IgY precipitation reagent
85R-1010	Fitzgerald	4 ml	EUR 554
Description: Chicken IgY precipitation reagent for use in immunoassays

Folin & Ciocalteu’s phenol reagent
abx082175-50ml	Abbexa	50 ml	EUR 189
Shipped within 5-10 working days.

Creatinine Color Reagent, 28ML
C004-28ML	Arbor Assays	28ML	EUR 268

GST Detection Reagent, 1EA
C035-1EA	Arbor Assays	1EA	EUR 237

Hemoglobin Detection Reagent, 20ML
C038-20ML	Arbor Assays	20ML	EUR 258

Hydrogen Peroxide Reagent, 5ML
C115-5ML	Arbor Assays	5ML	EUR 123

Fluorescent Detection Reagent, 5ML
C116-5ML	Arbor Assays	5ML	EUR 268

Hydrogen Peroxide Reagent, 5ML
C132-5ML	Arbor Assays	5 ML	EUR 123

FRAP Reagent A, 1.4ML
C148-1.4ML	Arbor Assays	1.4ML	EUR 178

FRAP Reagent B, 1.4ML
C149-1.4ML	Arbor Assays	1.4ML	EUR 178

EZ Cap? Reagent AG
B8176-.01	ApexBio	10 µl (100 mM)	EUR 308
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.05	ApexBio	50 µl (100 mM)	EUR 1240
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.1	ApexBio	100 µl (100 mM)	EUR 2214
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent GG
B8177-.01	ApexBio	10 µl (100 mM)	EUR 308
Description: EZ Cap Reagent GG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA resulting in a Cap 1 structure. EZ Cap GG requires a GG initiator. EZ Cap GG typically provides >90% capped material generating a natural Cap 1 structure.

EZ Cap? Reagent GG
B8177-.05	ApexBio	50 µl (100 mM)	EUR 1240
Description: EZ Cap Reagent GG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA resulting in a Cap 1 structure. EZ Cap GG requires a GG initiator. EZ Cap GG typically provides >90% capped material generating a natural Cap 1 structure.

Sapphire Insect Transfection Reagent
ABP-BVD-10003	Allele Biotech	75ul, 25 transfections	Ask for price
Product line: Sapphire Baculovirus Brand: Insect Transfection Kits

Biotin-XX Tyramide Reagent
A8012-10	ApexBio	10 mg	EUR 166
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-100	ApexBio	100 mg	EUR 862
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-1000	ApexBio	1 g	EUR 2602
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

ABTS Soluble Reagent (Aqueous)
ABT125	ScyTek Laboratories	125 ml	EUR 80

ABTS Soluble Reagent (Aqueous)
ABT500	ScyTek Laboratories	500 ml	EUR 138

ABTS Soluble Reagent (Aqueous)
ABT999	ScyTek Laboratories	1000 ml	EUR 205

Carrez Clarification Reagent Kit
K809-100	Biovision		EUR 245

iMFectin DNA Transfection Reagent
I7100-100	GenDepot	100ul	EUR 147

‘Viosinho’ (white selection), and 23.four min, 84.2°C, and 63.8% for var. ‘Touriga Nacional’ (pink selection). The achievement of optimum extraction situations of phenolics from grape stems utilizing solvents suitable with additional makes use of in meals/pharma industries demonstrated that RSM constitutes a robust device for deriving optimum situations for extraction of antioxidant phenolic compounds from grape stems.