Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline.

Schistosomiasis, certainly one of 17 illnesses deemed to be uncared for by the World Well being Group, has acquired little consideration from the biopharmaceutical business. As a result of this, solely a handful of medication have been developed to deal with schistosomiasis, with just one, praziquantel, utilized in most endemic areas. Rising concern over resistance coupled with praziquantel’s incomplete efficacy throughout all phases of the Schistosoma platyhelminth life cycle highlights the pressing want for brand spanking new medication.

The WIPO Re:Search consortium is a platform whereupon biopharmaceutical firm compounds are being repurposed to effectively and cost-effectively develop new medication for uncared for illnesses resembling schistosomiasis. This text summarizes latest clinical-stage efforts to determine new antischistosomals and highlights biopharmaceutical firm compounds with potential for repurposing to deal with schistosomiasis.

Flavonoids on the pharma-nutrition interface: Is a therapeutic index in demand?

The consumption of flavonoid-rich meals may have useful results on well being. Nevertheless, totally different lessons of flavonoids have totally different impact on illness threat and the connection between flavonoid consumption and threat of illness seemed to be non-linear. Moreover, contrarily to nutritional vitamins, there aren’t any signs of deficiency for flavonoids; due to this fact, our physique treats them like different xenobiotics. Due to this fact, a therapeutic index must be decided. Regardless of flavonoids are on the pharma-nutrition interface, medication and meals are topic to totally different regulatory frameworks and there’s no really helpful each day allowance (RDA) for flavonoids.

Comparatively little is understood in regards to the efficacy, security and underlying mechanisms of those bioactive compounds, particularly when taken in live performance with medication. Flavonoids may act each as medication and pro-drugs with pharmacological and toxicological promiscuity. As a result of low bioavailability, the gastrointestinal tract may very well be the first goal of flavonoids and metabolites. Completely different results have been noticed after acute and power consumption and bioavailability and bioactivity have excessive inter-individual variability.

Moreover, the difficulties within the design and within the interpretation of human intervention research make troublesome the institution of a therapeutic index for flavonoids. Most likely the idea of ‘personalised diet’ beforehand proposed may very well be the higher strategy. Nevertheless, regardless of extra research are wanted with the intention to set up a therapeutic index for every flavonoid subclasses, for the time being RDA of whole flavonoids may very well be between 250-400 mg/d, respecting the seasonality of meals sources.

High quality compliance within the shift from cell transplantation to cell remedy in non-pharma environments.

Together with educational and charitable organizations, transfusion facilities have ventured into the stem cell discipline, with the intention of testing of novel cell-based therapeutics in a scientific setting for future advertising and marketing approval. The truth that high quality administration constructions, that are required for compliance with good scientific follow rules, have been initially designed for product improvement in company environments represents a serious problem for a lot of builders. On this Commentary, challenges that non-pharmaceutical establishments should overcome to translate cell-based merchandise into scientific therapies can be mentioned from a high quality standpoint. Moreover, our improvement expertise for a mesenchymal stromal cell-based remedy can be shared as a case research.

Nanomedicine: a pharma perspective.

Nanotechnology as utilized to drugs is just not a brand new discipline. The primary nanomedicines accredited to be used have been developed from analysis relationship again to the 1970s. These liposomal formulations of current medication confirmed improved therapeutic exercise and decreased toxicity within the nonclinical mannequin methods. Nevertheless, these advantages proved extra refined and tougher to show in sufferers. This reality, mixed with the technical challenges in commercial-scale manufacturing of nanoparticles, led to solely restricted funding in nanomedicines by the key pharmaceutical corporations.

Even so, analysis on nanomedicines has proceeded apace in educational laboratories and smaller biopharmaceutical corporations. New supplies and drug mixtures have been studied, and concentrating on moieties added with the intention of enhancing the therapeutic index. Right now many of those new designs are in, or are approaching, scientific testing. It’ll take just one or two to achieve success to vary the best way pharmaceutical corporations view this discipline of revolutionary analysis.

Evaluation of (poly)phenols in grape (Vitis vinifera L.) stems through the use of meals/pharma business suitable solvents and Response Floor Methodology.

A Field-Behnken design of Response Floor Methodology (RSM) was carried out to analyse the impact of time (10-30 min), temperature (25-95°C), and solvents focus (5-90%) on the extraction of whole phenolics, flavonoids, ortho-diphenols, and anthocyanins in addition to to evaluate the ABTS(+) scavenging capability, which have been thought-about as response variables. Values coefficients of willpower (R(2)), starting from 0.903 to 0.996, fitted for describing environment friendly extraction of bioactive (poly)phenols and antioxidant exercise. The recorded knowledge allowed to ascertain the optimum extraction situations at 23.Zero min, 95.0°C, and 57.9% of food-quality ethanol/water for Vitis vinifera L. var.

Congo Red
HY-D0236	MedChemExpress	500mg	EUR 159.6

THERMAL PRINTER PAPER
GD-PAPER	CORNING	1/pk	EUR 224.4
Description: Lab Equipment; Axygen Branded EQ

Congo Red Powder
abx090680-5g	Abbexa	5 g	EUR 226.8

Congo Red Solution
CRA030	ScyTek Laboratories	30 ml	EUR 88.8

Congo Red Solution
CRA500	ScyTek Laboratories	500 ml	EUR 127.2

Congo Red Solution
CRA999	ScyTek Laboratories	1000 ml	EUR 171.6

Congo Red (C.I. 22120)
GT5674-100G	Glentham Life Sciences	100 g	EUR 74.4

Congo Red (C.I. 22120)
GT5674-250G	Glentham Life Sciences	250 g	EUR 103.2

Congo Red (C.I. 22120)
GT5674-25G	Glentham Life Sciences	25 g	EUR 54

Congo Red Indicator 0.1%
COR01001	Scientific Laboratory Supplies	1L	EUR 241.68

Congo Red Indicator 0.1%
COR01005	Scientific Laboratory Supplies	500ML	EUR 71.82

Congo Red Indicator 1%
COR1005	Scientific Laboratory Supplies	500ML	EUR 88.92

Congo Red Indicator 0.1%
COR105	Scientific Laboratory Supplies	500ML	EUR 71.82

Congo Red "high purity grade"
80028	Biotium	100MG	EUR 206.4
Description: Minimum order quantity: 1 unit of 100MG

Amyloid Stain Kit (Congo Red)
AMY-1	ScyTek Laboratories	1 kit(s)	EUR 198

Amyloid Stain Kit (Congo Red)
AMY-2	ScyTek Laboratories	1 kit(s)	EUR 130.8

FD Congo Red Solution™
PS108	FD Neurotechnologies	500 ml	EUR 284.4

USP Sol. Congo Red TS
USP1901	Scientific Laboratory Supplies	100ML	EUR 57

USP Sol. Congo Red TS
USP1905	Scientific Laboratory Supplies	500ML	EUR 94.62

EP Reagent Mercuric Bromide Paper
1052101	Scientific Laboratory Supplies	PK50	EUR 243.96

EP Reagent Lead Acetate Paper
R1048102	Scientific Laboratory Supplies	PK50	EUR 243.96

Johnson Litmus Red Paper
PAP1130	Scientific Laboratory Supplies	PK10	EUR 7.13

Pharmacopoeia 1M Cupriethylenediamine
3008700	Scientific Laboratory Supplies	1L	EUR 288.42

EP Reagent Ruthenium Red Sol.
1075201	Scientific Laboratory Supplies	100ML	EUR 103.74

Whatman Red Litmus Indicator Paper
PAP1024	Scientific Laboratory Supplies	PK10	EUR 84.36

Congo Red *UltraPure grade* *CAS 573-58-0*
23056	AAT Bioquest	100 mg	EUR 138

EP Reagent Methyl Red Mixed Sol.
1055101	Scientific Laboratory Supplies	100ML	EUR 42.18

EP Reagent Phenol Red Sol. R2
1063603	Scientific Laboratory Supplies	500ML	EUR 79.8

CP Reagent Coloration Primary Solution Red
CPPR01	Scientific Laboratory Supplies	100ML	EUR 166.44

SLS Select Indicator Paper Red Litmus
PAP1002	Scientific Laboratory Supplies	PK10	EUR 9.37

EP Reagent Indicator Sol. Methyl Red 0.02%
1055102	Scientific Laboratory Supplies	100ML	EUR 42.18

Whatman Red Litmus 6mmx5m Roll Indicator Paper
PAP1116	Scientific Laboratory Supplies	EACH	EUR 18.24

EP Reagent Bromocresol Green Methyl Red Mixed Indicator
1012602	Scientific Laboratory Supplies	100ML	EUR 42.18

EP Reagent Bromocresol Green - Methyl Red Mixed Indicator
10126021	Scientific Laboratory Supplies	1L	EUR 210.9

EP Reagent Bromocresol Green - Methyl Red Mixed Indicator
10126025	Scientific Laboratory Supplies	5L	EUR 330.6

EP Reagent Biuret Reagent
1011601	Scientific Laboratory Supplies	1L	EUR 42.18

EP Reagent Iodoplatinate Reagent
1046300	Scientific Laboratory Supplies	200ML	EUR 360.24

EP Reagent Methoxyphenylacetic Reagent
1053601	Scientific Laboratory Supplies	100ML	EUR 354.54

EP Reagent Molybdovanadic Reagent
1056700	Scientific Laboratory Supplies	100ML	EUR 42.18

EP Reagent Phosphomolybdotungstic Reagent
1065000	Scientific Laboratory Supplies	100ML	EUR 161.88

EP Reagent Sulfomolybdic Reagent R3
1086500	Scientific Laboratory Supplies	1L	EUR 287.28

BOP reagent
5-02141	CHI Scientific	25g	Ask for price

BOP reagent
5-02142	CHI Scientific	100g	Ask for price

Chymase reagent
30C-CP1129	Fitzgerald	5 units	EUR 2622
Description: Purified native Human Chymase reagent

Traut's Reagent
2330-1000	Biovision		EUR 418.8

Traut's Reagent
2330-500	Biovision		EUR 248.4

MTS Reagent
2808-1000	Biovision		EUR 1188

MTS Reagent
2808-250	Biovision		EUR 438

MTT Reagent
2809-1G	Biovision		EUR 216

MTT Reagent
2809-5G	Biovision		EUR 652.8

BOP reagent
A7015-100000	ApexBio	100 g	EUR 240
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

BOP reagent
A7015-25000	ApexBio	25 g	EUR 135.6
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Bradford reagent
BDE641	Bio Basic	100ml	EUR 73.21

Bluing Reagent
BRT030	ScyTek Laboratories	30 ml	EUR 72

Bluing Reagent
BRT125	ScyTek Laboratories	125 ml	EUR 75.6

Bluing Reagent
BRT3800	ScyTek Laboratories	1 Gal.	EUR 220.8

Bluing Reagent
BRT500	ScyTek Laboratories	500 ml	EUR 91.2

Bluing Reagent
BRT999	ScyTek Laboratories	1000 ml	EUR 105.6

Beaucage reagent
HY-100951	MedChemExpress	10mM/1mL	EUR 151.2

Phosphate Reagent
106199	Scientific Laboratory Supplies	PK100	EUR 61.29

Chromium Reagent
1206699	Scientific Laboratory Supplies	EACH	EUR 141.72

Ninhydrin Reagent
MIC6746	Scientific Laboratory Supplies	EACH	EUR 31.12

Nessler Reagent
NESSR	Scientific Laboratory Supplies	500ML	EUR 148.2

Thioacetamide Reagent
THIOR01	Scientific Laboratory Supplies	100ML	EUR 78.66

Phenophalein paper
PAP1120	Scientific Laboratory Supplies	EACH	EUR 18.24

Motor for hub paper feed cleaning paper
WAT4708	Scientific Laboratory Supplies	EACH	EUR 311.22

Biotin reagent (HRP)
65C-CE0202	Fitzgerald	5 mg	EUR 292.8
Description: HRP conjugated biotin labelling reagent

Convoy? Transfection Reagent
1110-1ml	ACTGene		EUR 409.2

Bradford Dye Reagent
0209R	AthenaES	100 ml	EUR 157.2

BSA (Reagent Grade)
30-AB79	Fitzgerald	1 kg	EUR 1862.4
Description: Reagent Grade Bovine Serum Albumin (99% pure)

BSA (Reagent Grade)
30-AB81	Fitzgerald	200 grams	EUR 571.2
Description: Reagent Grade Sulphydryl Blocked BSA (99% pure)

Griess Reagent Kit
30100	Biotium	1KIT	EUR 178.8
Description: Minimum order quantity: 1 unit of 1KIT

BODIPY-Acetylene Reagent
2594-1	Biovision		EUR 248.4

BODIPY-Acetylene Reagent
2594-5	Biovision		EUR 810

EL Transfection Reagent
20-abx098880	Abbexa	EUR 460.80 EUR 644.40	0.75 ml 1.5 ml

Mycoplasma Prevention Reagent
20-abx098886	Abbexa	EUR 510.00 EUR 610.80	1 ml 5 ml

FcR blocking Reagent
20-abx290024	Abbexa	EUR 452.40 EUR 619.20	200 tests 400 tests

Detection Reagent A
abx296004-120ul	Abbexa	120 ul	EUR 385.2

Mycoplasma Prevention Reagent
20-abx298005	Abbexa	EUR 243.60 EUR 343.20	1 ml 5 ml

Girard's reagent T
20-abx184099	Abbexa	EUR 243.60 EUR 376.80	100 g 500 g

HAMA blocking reagent
85R-1001	Fitzgerald	1 gram	EUR 2368.8
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1001P	Fitzgerald	1 gram	EUR 2628
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent
85R-1003	Fitzgerald	1 gram	EUR 2368.8
Description: HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

HAMA blocking reagent
85R-1014	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in assays specific for clinical false positive samples

HAMA blocking reagent
85R-1025	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in immunoassays

HAMA blocking reagent
85R-1026	Fitzgerald	50 mg	EUR 230.4
Description: HAMA blocking reagent for use in immunoassays

PhosphoBlocker Blocking Reagent
AKR-103	Cell Biolabs	1L	EUR 393.6
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

PhosphoBlocker Blocking Reagent
AKR-104	Cell Biolabs	4L	EUR 853.2
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

Biolipidure-1002-Reagent
Biolipidure-1002-10	Cusabio	10mL	EUR 235.2
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1002-Reagent
Biolipidure-1002-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent
Biolipidure-103-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent
Biolipidure-1201-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent
Biolipidure-1301-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent
Biolipidure-203-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent
Biolipidure-206-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent
Biolipidure-405-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent
Biolipidure-502-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent
Biolipidure-702-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-10	Biolipidure	10mL	EUR 235.2
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent
Biolipidure-802-100	Biolipidure	100mL	EUR 1467.6
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Specimen Preservation Reagent
DA0970	Daan Gene	100 test/kit	Ask for price

DTT (Cleland's reagent)
DB0058	Bio Basic	5g	EUR 101.76

DTNB (Ellman's Reagent)
DB0113	Bio Basic	5g	EUR 117.42

BCA Reagent, 16ML
C144-16ML	Arbor Assays	16ML	EUR 195.6

Ethyl acetate Reagent
EC4600	Bio Basic	1L	EUR 94.8

Alcohol, Reagent (70%)
EAS500	ScyTek Laboratories	500 ml	EUR 94.8

Alcohol, Reagent (70%)
EAS999	ScyTek Laboratories	1000 ml	EUR 121.2

LP4K Transfection Reagent
LP4K	GenTarget	1.0 ml / vial	EUR 364.8
Description: Lipid based transfection reagent for large plasmid and multiple plasmid transfection in both adhesive and suspenstion cell types.

PureFection Transfection Reagent
LV750A-1	SBI	1 ml	EUR 430.8

n-Heptane Reagent
HC5400	Bio Basic	1L	EUR 94.8

Tri-RNA Reagent
FATRR-001	Favorgen	100ml	EUR 283.2

Tri-RNA Reagent
FATRR-002	Favorgen	50ml	EUR 211.2

Tri-RNA Reagent
FATRR-003	Favorgen	450ml	EUR 774

ExFect2000 Transfection Reagent
T202-01	Vazyme	0.5 ml	EUR 272.4

ExFect2000 Transfection Reagent
T202-02	Vazyme	1 ml	EUR 379.2

ExFect2000 Transfection Reagent
T202-03	Vazyme	5 ml	EUR 1262.4

TissueDigest Reagent, 20X
T101	Insitus Biotechnologies	10ml	EUR 252

HighGene transfection reagent
RM09014	Abclonal	1000μl	EUR 324

DeStreak reagent 1mL
17600318	Scientific Laboratory Supplies	EACH	EUR 69.54

SulfaVer 4 Reagent
2106769	Scientific Laboratory Supplies	PK100	EUR 70.22

Citric Acid Reagent
2254232	Scientific Laboratory Supplies	EACH	EUR 47.24

Catalase Reagent Dropper
261203	Scientific Laboratory Supplies	PK50	EUR 70.68

Silica 3 Reagent
27169	Scientific Laboratory Supplies	100ML	EUR 89.38

EP Reagent Ferroin
1038100	Scientific Laboratory Supplies	100ML	EUR 77.52

TDA Reagent - 10mL
MIC6732	Scientific Laboratory Supplies	EACH	EUR 26.33

PYR Reagent - 10mL
MIC6744	Scientific Laboratory Supplies	EACH	EUR 31.12

Dissociation Reagent, 1ML
X017-1ML	Arbor Assays	1ML	EUR 130.8

Dissociation Reagent, 25ML
X017-25ML	Arbor Assays	25ML	EUR 309.6

Dissociation Reagent, 5ML
X017-5ML	Arbor Assays	5ML	EUR 146.4

Dissociation Reagent, 1ML
X058-1ML	Arbor Assays	1ML	EUR 87.6

Dissociation Reagent, 5ML
X058-5ML	Arbor Assays	5ML	EUR 130.8

Folin-Ciocalteus Reagent
FOCIRE01	Scientific Laboratory Supplies	100ML	EUR 95.76

Reagent Reservoir 50ml
F267670	Scientific Laboratory Supplies	PK100	EUR 232.56

Olsens Mixed Reagent
OLSMR01	Scientific Laboratory Supplies	1L	EUR 135.66

Hanna Phosphorous Reagent
WAT1513	Scientific Laboratory Supplies	PK100	EUR 38.87

Hanna Bromine Reagent
WAT1535	Scientific Laboratory Supplies	EACH	EUR 30.78

Hanna Nitrate Reagent
WAT1547	Scientific Laboratory Supplies	EACH	EUR 86.64

Palintest Reagent Nitrate
WAT8098	Scientific Laboratory Supplies	PK200	EUR 144.78

Ammonia Monitor Reagent
ROREA10	Scientific Laboratory Supplies	10L	EUR 202.92

Whatman pH Paper 1-11x1.0 units Indicator Paper
PAP1010	Scientific Laboratory Supplies	PK100	EUR 104.88

Crimean-Congo hemorrhagic fever virus Nucleoprotein (N)
1-CSB-EP328701CSB	Cusabio	EUR 733.20 EUR 370.80 EUR 2192.40 EUR 1126.80 EUR 1461.60 EUR 476.40	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Crimean-Congo hemorrhagic fever virus Nucleoprotein(N) expressed in E.coli

Crimean-Congo hemorrhagic fever virus PCR kit
PCR-VH060-48R	Bioingentech	50T	EUR 987.6

Crimean-Congo hemorrhagic fever virus PCR kit
PCR-VH060-96R	Bioingentech	100T	EUR 1335.6

Paper Roll Adhesive
BAL4001	Scientific Laboratory Supplies	PK3	EUR 28.04

Replacement printer paper
MOL3552	Scientific Laboratory Supplies	EACH	EUR 44.46

Paper Chromatography 460X570mm
CJ32040	Scientific Laboratory Supplies	PK25	EUR 289.56

Absorbent paper roll
DD30640	Scientific Laboratory Supplies	EACH	EUR 21.66

Thermal Paper Matt
ELE5013	Scientific Laboratory Supplies	EACH	EUR 23.94

Spare Printer Paper
SPE3098	Scientific Laboratory Supplies	PK20	EUR 104.88

Blotting Paper Sheets
F3030-6188	Scientific Laboratory Supplies	PK100	EUR 57

Lead acetete paper
PAP1122	Scientific Laboratory Supplies	EACH	EUR 20.52

SPIKED FILTER PAPER
CFM-SPIKE-1	Scientific Laboratory Supplies	EACH	EUR 136.8

Whatman weighing paper
Z134112-500EA	Scientific Laboratory Supplies	PK500	EUR 35.34

European Pesticide Mix 2017-170 100 ug/mL (100 ppm) 1mLin Acetonitrile.
EU-2017-170	Scientific Laboratory Supplies	1ML	EUR 67.26

Crimean-Congo hemorrhagic fever virus RT PCR kit
RTq-VH060-100R	Bioingentech	100T	EUR 1573.2

Crimean-Congo hemorrhagic fever virus RT PCR kit
RTq-VH060-150R	Bioingentech	150T	EUR 2144.4

Crimean-Congo hemorrhagic fever virus RT PCR kit
RTq-VH060-50R	Bioingentech	50T	EUR 1155.6

Biotin reagent (Alk Phos)
65C-CE0201	Fitzgerald	1 mg	EUR 253.2
Description: Alkaline Phosphatase conjugated biotin labelling reagent

Biotin reagent (Glucose Oxidase)
65C-CE0203	Fitzgerald	5 mg	EUR 278.4
Description: Glucose Oxidase conjugated biotin labelling reagent

Annexin V-FITC Reagent
1001-1000	Biovision		EUR 1495.2

Annexin V-FITC Reagent
1001-200	Biovision		EUR 529.2

Annexin V-Cy3 Reagent
1002-1000	Biovision		EUR 1358.4

Annexin V-Cy3 Reagent
1002-200	Biovision		EUR 483.6

Annexin V-Biotin Reagent
1003-100	Biovision		EUR 444

Annexin V-Biotin Reagent
1003-1000	Biovision		EUR 2865.6

Annexin V-EGFP Reagent
1004-1000	Biovision		EUR 1358.4

Annexin V-EGFP Reagent
1004-200	Biovision		EUR 483.6

DIRECTPCR LYSIS REAGENT (TAIL)
101-T	Cusabio	50 ml	EUR 169.2
Description: Up to 250 tails (50ml)

Annexin V-Cy5 Reagent
1013-1000	Biovision		EUR 1358.4

Annexin V-Cy5 Reagent
1013-200	Biovision		EUR 483.6

Annexin V-PE Reagent
1014-1000	Biovision		EUR 1358.4

Annexin V-PE Reagent
1014-200	Biovision		EUR 483.6

DIRECTPCR LYSIS REAGENT (TAIL)
102-T	Viagen	100ml	EUR 248.4
Description: Up to 500 tails (50ml)

DIRECTPCR LYSIS REAGENT (EAR)
401-E	Viagen	25 ml	EUR 169.2
Description: For use with ear pieces

DIRECTPCR LYSIS REAGENT (EAR)
402-E	Viagen	50 ml	EUR 248.4
Description: For use with ear pieces

Mouse IgG Blocking Reagent
30R-AH071	Fitzgerald	20 mg	EUR 309.6
Description: Mouse IgG (H + L) Blocking Reagent

MESG *Phosphate assay reagent*
21600	AAT Bioquest	5 mg	EUR 138

DIRECTPCR LYSIS REAGENT (CELL)
301-C	Viagen	50 ml	EUR 169.2
Description: For use with cultured cells

DIRECTPCR LYSIS REAGENT (CELL)
302-C	Viagen	100 ml	EUR 248.4
Description: For use with cultured cells

Folin & Ciocalteu’s phenol reagent
abx082175-50ml	Abbexa	50 ml	EUR 226.8

ABTS Soluble Reagent (Aqueous)
ABT125	ScyTek Laboratories	125 ml	EUR 96

ABTS Soluble Reagent (Aqueous)
ABT500	ScyTek Laboratories	500 ml	EUR 165.6

ABTS Soluble Reagent (Aqueous)
ABT999	ScyTek Laboratories	1000 ml	EUR 246

Biotin-XX Tyramide Reagent
A8012-10	ApexBio	10 mg	EUR 199.2
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-100	ApexBio	100 mg	EUR 1034.4
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Biotin-XX Tyramide Reagent
A8012-1000	ApexBio	1 g	EUR 3122.4
Description: Biotin-LC-LC-tyramide is used for tyramide signal amplification (TSA) which is a powerful, patented technology that significantly enhances both chromogenic and fluorescent signals. TSA is easily integrated into standard nonradioactive in situ hybridization (ISH) or IHC protocols

Sapphire Insect Transfection Reagent
ABP-BVD-10003	Allele Biotech	75ul, 25 transfections	Ask for price

Chicken IgY precipitation reagent
85R-1010	Fitzgerald	4 ml	EUR 664.8
Description: Chicken IgY precipitation reagent for use in immunoassays

EZ Cap? Reagent AG
B8176-.01	ApexBio	10 µl (100 mM)	EUR 369.6
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.05	ApexBio	50 µl (100 mM)	EUR 1488
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

EZ Cap? Reagent AG
B8176-.1	ApexBio	100 µl (100 mM)	EUR 2656.8
Description: EZ Cap Reagent AG is a co-transcriptional capping reagent for in vitro transcription of 5? capped mRNA which would result in a Cap 1 structure. Cap AG has shown to provide up to 98% capping efficiency in literatures.EZ Cap AG requires an AG initiator.

‘Viosinho’ (white selection), and 23.four min, 84.2°C, and 63.8% for var. ‘Touriga Nacional’ (pink selection). The achievement of optimum extraction situations of phenolics from grape stems utilizing solvents suitable with additional makes use of in meals/pharma industries demonstrated that RSM constitutes a robust device for deriving optimum situations for extraction of antioxidant phenolic compounds from grape stems.